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Aminopurvalanol A

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Purity:99.64%

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COA HNMR LCMS

Aminopurvalanol A

Catalog No. T22260Cas No. 220792-57-4

Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1, Cyclin E/cdk2, and P35/cdk5 with IC50 of 33 nM, 33 nM, 28 nM and 20 nM, respectively.

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Pack Size	Price	Availability
1 mg	$41	In Stock
2 mg	$59	In Stock
5 mg	$97	In Stock
10 mg	$163	In Stock
25 mg	$322	In Stock
50 mg	$497	In Stock
100 mg	$723	In Stock
500 mg	$1,520	In Stock
1 mL x 10 mM (in DMSO)	$98	In Stock

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	403.91
Formula	C19H26ClN7O
Cas No.	220792-57-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

Ethanol: 10 mg/mL (24.76 mM）, Sonication is recommended.

DMSO: 55 mg/mL (136.17 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4758 mL	12.3790 mL	24.7580 mL	123.7900 mL
5 mM	0.4952 mL	2.4758 mL	4.9516 mL	24.7580 mL
10 mM	0.2476 mL	1.2379 mL	2.4758 mL	12.3790 mL
20 mM	0.1238 mL	0.6189 mL	1.2379 mL	6.1895 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0495 mL	0.2476 mL	0.4952 mL	2.4758 mL
100 mM	0.0248 mL	0.1238 mL	0.2476 mL	1.2379 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc